Brief History: The seeds for the T-cell Modulation Group were sown at the University of Oxford in late 1995 in the Nuffield Department of Medicine. The group moved to Cardiff University in 2006 and can now be found in the Henry Wellcome Building in the Division of Infection and Immunity, School of Medicine.
What we do: The T-cell Modulation Group consists of researchers with a diverse skill and knowledge base that covers all areas of T-cell biology including T-cell genetics, molecular biology, protein chemistry, crystallography, cell biology and clinical investigations. The overall goal of the T-cell Modulation Group is to understand the genetic, biochemical and cellular mechanisms that govern T-cell responses to human disease. Our research outputs are extremely wide ranging and include basic studies which are aimed at understanding how the T-cell immune response is regulated, through to translational studies which are aimed at developing tools, diagnostics and treatments for human diseases such as cancer, diabetes, HIV, tuberculosis, EBV and many more.
Who we are: The T-cell Modulation Group currently has 16 members including 2 post-doctoral fellows, 2 research associates and 6 post-graduate students. We work with numerous collaborators as close to home as the teams upstairs and as far afield as Australia to comprehensively investigate key questions involving T-cell biology.
The group has 10 active research projects in areas such as, cancer immunotherapy, transplant rejection, tuberculosis, autoimmunity and pathogen detection.